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. 2024 Jan 2;19(1):e0287840. doi: 10.1371/journal.pone.0287840

Table 8. Toxicity prediction of compounds identified from raw and roasted Terminalia catappa nuts.

Compounds LD50
(mg/kg)
Toxicity
class
Hepato-
toxicity
Carcino-
genicity
Immuno-
genicity
Muta-
genicity
Cyto-
toxicity
Proanthocyanin 2500 5 - - + - -
Naringin 2300 5 - - + - -
Quinine 263 3 - - + - -
Flavan-3-ol 2500 5 - - - - -
Anthocyanin 2500 5 - + - + -
Ribalinidine 150 3 - - + + -
Naringenin 2000 4 - - - - +
Spartein 220 3 - - + - -
Sapogenin 2500 5 - + + - -
Phenol 270 3 - - - - -
Flavonones 2000 4 - + - - +
Steroid 3000 5 - - + - -
Epicatechin 10000 6 - - - - -
Kaempferol 3919 5 - - - - -
Phytate 1500 4 - - - - -
Flavone 2500 5 - + - - -
Oxalate 660 4 - - - - -
Catechin 10000 6 - - - - -
Resveratrol 1560 4 - - - - -
Tannin 2260 5 - - - - -

Key: LD50 = lethal median dose; (+) = Active; (—) = inactive.