Table 8. Toxicity prediction of compounds identified from raw and roasted Terminalia catappa nuts.
Compounds | LD50 (mg/kg) |
Toxicity class |
Hepato- toxicity |
Carcino- genicity |
Immuno- genicity |
Muta- genicity |
Cyto- toxicity |
---|---|---|---|---|---|---|---|
Proanthocyanin | 2500 | 5 | - | - | + | - | - |
Naringin | 2300 | 5 | - | - | + | - | - |
Quinine | 263 | 3 | - | - | + | - | - |
Flavan-3-ol | 2500 | 5 | - | - | - | - | - |
Anthocyanin | 2500 | 5 | - | + | - | + | - |
Ribalinidine | 150 | 3 | - | - | + | + | - |
Naringenin | 2000 | 4 | - | - | - | - | + |
Spartein | 220 | 3 | - | - | + | - | - |
Sapogenin | 2500 | 5 | - | + | + | - | - |
Phenol | 270 | 3 | - | - | - | - | - |
Flavonones | 2000 | 4 | - | + | - | - | + |
Steroid | 3000 | 5 | - | - | + | - | - |
Epicatechin | 10000 | 6 | - | - | - | - | - |
Kaempferol | 3919 | 5 | - | - | - | - | - |
Phytate | 1500 | 4 | - | - | - | - | - |
Flavone | 2500 | 5 | - | + | - | - | - |
Oxalate | 660 | 4 | - | - | - | - | - |
Catechin | 10000 | 6 | - | - | - | - | - |
Resveratrol | 1560 | 4 | - | - | - | - | - |
Tannin | 2260 | 5 | - | - | - | - | - |
Key: LD50 = lethal median dose; (+) = Active; (—) = inactive.