Table 4.
Mean and mean difference in left ventricular mass index among all participants with sustained normotension, white coat, masked, or sustained hypertension and among all participants with sustained controlled blood pressure, white coat effect, masked uncontrolled hypertension, and sustained uncontrolled blood pressure according to blood pressure thresholds in the 2017 ACC/AHA and JNC7 guidelines.
| Not taking antihypertensive medication (n=432) | Taking antihypertensive medication (n=285) | ||||
|---|---|---|---|---|---|
| Phenotype by guideline | Mean (SD) | Adjusted mean differencea (95% confidence interval) |
Phenotype by guideline | Mean (SD) | Adjusted mean differencea (95% confidence interval) |
| 2017 ACC/AHA | 2017 ACC/AHA | ||||
| Sustained normotension | 33.9 (8.1) | 0 (ref) | Sustained controlled BP | 41.3 (12.6) | 0 (ref) |
| White coat hypertension | 35.5 (7.1) | −0.90 (−5.68, 3.88) | White coat effect | 46.6 (12.6) | 3.17 (−3.84, 10.18) |
| Masked hypertension | 36.0 (9.4) | 1.96 (−0.16, 4.07) | Masked uncontrolled hypertension | 42.0 (13.1) | −0.43 (−4.66, 3.81) |
| Sustained hypertension | 40.2 (9.6) | 4.51 (2.27, 6.74) | Sustained uncontrolled BP | 47.5 (14.6) | 5.18 (1.37, 8.99) |
| JNC7 | JNC7 | ||||
| Sustained normotension | 34.5 (8.7) | 0 (ref) | Sustained controlled BP | 42.1 (11.9) | 0 (ref) |
| White coat hypertension | 33.1 (6.3) | −2.06 (−7.96, 3.84) | White coat effect | 41.1 (12.2) | 2.78 (−9.61, 15.17) |
| Masked hypertension | 38.6 (8.4) | 3.00 (0.97, 5.02) | Masked uncontrolled hypertension | 44.2 (15.0) | 1.01 (−2.56, 4.57) |
| Sustained hypertension | 41.6 (12.1) | 5.57 (2.53, 8.61) | Sustained uncontrolled BP | 50.7 (15.1) | 7.08 (2.76, 11.40) |
| p-valuesb | |||||
| White coat hypertension | 0.469 | White coat effect | 0.937 | ||
| Masked hypertension | 0.398 | Masked uncontrolled hypertension | 0.389 | ||
| Sustained hypertension | 0.500 | Sustained uncontrolled BP | 0.338 | ||
BP: blood pressure.
SD: standard deviation.
ACC/AHA: American College of Cardiology/American Heart Association Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults.
JNC7: The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure.
Adjusted for field center, age, sex, race, education less than high school, current smoking, body mass index, low and high-density lipoprotein cholesterol, diabetes, reduced estimated glomerular filtration rate, and albuminuria.
P-value comparing the difference in left ventricular mass index among participants with white coat, masked, and sustained hypertension, and white coat effect, masked uncontrolled hypertension, and sustained uncontrolled BP defined using the 2017 ACC/AHA guideline versus the JNC7 guideline.