TABLE 3.
Lung function parameters obtained via spirometry at 6 months after hospital discharge in patients requiring veno-venous extracorporeal membrane oxygenation in the acute phase of coronavirus disease 2019 (Group COVID) and in healthy matched controls (Group H).
| Group H | Group COVID | p | ||
| FEV1 | Absolute value (liters) | 3.51 ± 0.89 | 2.68 ± 0.50 | 0.01 |
| % predicted | 97.6 ± 7.5 | 79.5 ± 18.2 | 0.02 | |
| Z score | -0.18 ± 0.56 | -1.54 ± 1.28 | 0.01 | |
| FVC | Absolute value (liters) | 4.39 ± 1.04 | 3.04 ± 0.45 | <0.001 |
| % predicted | 101.2 ± 7.8 | 73.4 ± 15.9 | <0.001 | |
| Z score | 0.05 ± 0.67 | -2.0 ± 1.18 | <0.001 | |
| FEV1/FVC | Absolute value (%) | 79.9 ± 4.7 | 87.9 ± 4.8 | 0.001 |
| % predicted | 100.0 ± 4.9 | 114.1 ± 10.0 | 0.05 | |
| Z score | 0.02 ± 0.71 | 1.09 ± 0.69 | 0.002 | |
| FEF25–75 | Absolute value (l/s) | 3.34 ± 0.98 | 4.05 ± 1.51 | 0.24 |
| % predicted | 93.2 ± 17.8 | 118.1 ± 41.5 | 0.12 | |
| Z score | -0.27 ± 0.61 | 0.57 ± 1.49 | 0.14 | |
| PEF | Absolute value (l/s) | 8.12 ± 1.43 | 7.50 ± 1.48 | 0.33 |
| % predicted | 98.9 ± 10.3 | 96.9 ± 20.0 | 0.78 | |
| Z score | -0.10 ± 0.7 | -0.23 ± 1.44 | 0.81 |
FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; FEF25–75, forced expiratory flow between 25 and 75% of the volume expired; PEF, peak expiratory flow. Data were expressed as absolute values, percent predicted, and Z-scores. Bold values: statistically significant difference.