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. 2023 Jun 27;26(1):85–97. doi: 10.1007/s12094-023-03219-0

Table 3.

AGREE-REX standardized domain scores: CPGs by SEOM (n= 28)

Guidelines [references] Domain (%) Mean score (SD)
D1
Clinical applicability
D2
Values and preferences
D3
Implementability
Breast (early stage) [23, 55] 77.8 45.8 65.5 63.0 (0.2)
Breast (advanced) [27, 60] 72.2 30.6 51.7 41.3 (0.1)
Colorectal (metastasic) [33, 66] 85.2 54.2 20.7 53.4 (0.0)
Colorectal (hereditary) [39, 65] 96.3 25.0 38.0 53.1 (0.4)
Endometrial [25, 57, 58] 35.2 19.4 27.6 27.4 (0.1)
Gastrointestinal sarcomas [48] 92.6 12.5 0.0 35.0 (0.5)
Glioblastoma [45] 98.2 27.8 13.8 46.6 (0.5)
Glioma (anaplasic) [24, 56] 64.8 5.6 34.5 35.0 (0.3)
Glioma (low grade) [54, 83] 87.0 34.7 58.6 60.1 (0.3)
Head and neck [46, 84, 85] 59.3 26.4 58.6 48.1 (0.2)
Hepatocellular [31, 62, 63] 92.6 56.9 82.8 77.4 (0.2)
Kidney [40, 8688] 77.8 26.4 44.8 49.7 (0.3)
Lung (small cell) [30] 88.9 29.1 31.0 49.7 (0.3)
Lung (non-small cell) [42, 89] 64.8 9.7 0.0 24.8 (0.3)
Lymphoma (follicular non-Hodgkin) [49] 70.4 45.8 62.1 59.4 (0.1)
Medulloblastoma [41] 79.6 27.8 62.1 56.5 (0.3)
Melanoma [43, 90, 91] 85.2 40.3 55.1 60.2 (0.2)
Mesothelioma [47] 92.6 27.8 0.0 40.1 (0.5)
Nasopharynx [53, 92] 75.9 29.2 62.1 55.7 (0.2)
Neuroendocrine [37, 93] 64.8 19.4 41.4 41.9 (0.2)
Ovarian [50, 94, 95] 94.5 37.5 17.2 49.7 (0.4)
Pancreatic and biliary [34, 96, 97] 66.7 27.8 44.8 46.4 (0.2)
Prostate [36, 98100] 72.2 34.7 44.8 50.6 (0.2)
Rectal [26, 59] 74.1 12.5 37.9 41.5 (0.3)
Sarcoma [28, 61] 75.9 29.2 17.3 40.1 (0.3)
Thymic epithelial [51] 75.9 27.8 69.0 57.6 (0.3)
Thyroid [32, 64] 55.6 27.8 69.0 50.8 (0.2)
Urothelial bladder [35, 101, 102] 87.0 18.1 27.6 44.2 (0.4)

Domain 1 “Clinical applicability”: Items 1.  Evidence, 2. Applicability to Target Users, 3. Applicability to Patients/Population; Domain 2 “Values and Preferences”: Items 4. Values and Preferences of Target Users, 5. Values and Preferences of Patients/Population, 6. Values and Preferences of Policy/Decision-makers, 7. Values and Preferences of Guideline Developers; Domain 3 “Implementability”: Items 8. Purpose, 9. Local application and Adoption.