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. 2023 Dec 14;15(1):104–107. doi: 10.1111/1759-7714.15155

FIGURE 2.

FIGURE 2

Pathological findings of retroperitoneal tissue (a, b: hematoxylin and eosin staining). Microscopic examination revealed lymphocytic infiltration with layered fibrosis (a: 40×, b: 400×) (c: immunohistochemistry [IHC] for IgG). IHC staining demonstrated the presence of IgG‐positive plasma cells (×100) (d: IHC for IgG4). IHC staining revealed the presence of numerous IgG4‐positive plasma cells. The number of IgG4‐positive cells corresponded to approximately 70% of the total number of IgG‐positive cells in the same area (100×) (e: IHC for CD3, f: IHC for CD20). Immunohistochemistry demonstrated that lymphocytes were positive for both CD3 (e: ×100) and CD20 (f: ×100), suggesting an association with both T and B cell lymphocytes (g: IHC for CD4, h: IHC for CD8). T cell lymphocytes infiltrating the lesion were positive for both CD4 and CD8 with a predominance of CD8.