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. 2024 Jan 2;76:1. doi: 10.1186/s43044-023-00430-w

Table 3.

Genotype frequencies in case versus control

Genotype N (%) Chi-square test Binary logistic regression
Control Case (CAD) Total χ2 Cramer’s V p value COR 95% CI p value
G/G 10 (10%) 3 (3%) 13 (6.5%) 7.668 0.196 0.022

r(1)

2.5

4.5

r(1)

0.63–9.9

1.2–17.1

0.191

0.029

G/T 40 (40%) 30 (30%) 70 (35%)
T/T 50 (50%) 67 (67%) 117 (58.5%)

Bold value indicate significance p ≤ 0.050

CAD coronary artery disease, COR crude odds ratio, CI confidence interval

r(1) = reference category

This table shows a statistically significantly higher proportion of ‘T/T’ genotype among cases versus control (risk genotype). This association is of low strength (Cramer’s V lies between 0.1 and 0.3). A participant with ‘T/T’ genotype has 4.5 times higher odds to exhibit ACS versus a participant with ‘G/G’ genotype