Table 3.
Genotype frequencies in case versus control
| Genotype | N (%) | Chi-square test | Binary logistic regression | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Control | Case (CAD) | Total | χ2 | Cramer’s V | p value | COR | 95% CI | p value | |
| G/G | 10 (10%) | 3 (3%) | 13 (6.5%) | 7.668 | 0.196 | 0.022 |
r(1) 2.5 4.5 |
r(1) 0.63–9.9 1.2–17.1 |
0.191 0.029 |
| G/T | 40 (40%) | 30 (30%) | 70 (35%) | ||||||
| T/T | 50 (50%) | 67 (67%) | 117 (58.5%) | ||||||
Bold value indicate significance p ≤ 0.050
CAD coronary artery disease, COR crude odds ratio, CI confidence interval
r(1) = reference category
This table shows a statistically significantly higher proportion of ‘T/T’ genotype among cases versus control (risk genotype). This association is of low strength (Cramer’s V lies between 0.1 and 0.3). A participant with ‘T/T’ genotype has 4.5 times higher odds to exhibit ACS versus a participant with ‘G/G’ genotype