Table 5.
Association of rs1122608 genotype and severity of CAD patients
| Cases | GG | GT | TT | P | |
|---|---|---|---|---|---|
| n = 3 | n = 30 | n = 67 | |||
| EF (%) | 57 ± 9.5 | 58 ± 12.5 | 55.4 ± 10.8 | 0.816 | |
| ECG | Average | 1 (33.3%) | 18 (60%) | 37 (55.2%) | 0.682 |
| Abnormal | 2 (66.7%) | 12 (40%) | 30 (44.8%) | ||
|
Uni vessel N = 57 |
2 (3.5%) | 18(31.6%) | 37 (64.9%) | 0.378 | |
|
Two vessels N = 31 |
1 (3.2%) | 11 (35.5%) | 19 (61.3%) | ||
|
More than two vessels N = 12 |
0 (0.0%) | 1 (8.3%) | 11 (91.7%) | ||
| Gensini score | 26.7 ± 19.7 | 32 ± 30.1 | 34.4 ± 29.5 | 0.863 | |
This table reveals no significant differences found regarding ejection fraction (EF), electrocardiograph (ECG) among rs1122608 genotypes in CAD group (p = 0.816, 0.682 respectively), no significant association is found between rs1122608 genotypes and alleles with extent of vessel affection (p = 0.378), in spite of increased frequency of TT genotype in CAD patients with multi-vessel affection more than those with one vessel and two vessel affected (91.7%, 61.3%, 64.9% respectively). As regard Gensini score, it shows no significant association with rs1122608 genotypes (p = 0.863)