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. 2024 Jan 2;14:58. doi: 10.1038/s41598-023-50931-6

Table 3.

Sensitivity analysis censoring the NED by multivariable Cox regression for mortality by centile of TC.

No. of patients Events Person-years Incidence rate (per 10,000 py) Age and sex-adjusted HR (95% CI) Multivariable-adjusted HR (95% CI)
1st–5th (≤ 97 mg/dL) 3012 894 10,467 854.2 1.86 (1.71–2.02) 1.60 (1.46–1.74)
6th–20th (97–128 mg/dL) 9217 2051 32,517 630.7 1.52 (1.42–1.62) 1.29 (1.20–1.38)
21st–40th (129–151 mg/dL) 12,006 2030 44,129 460.0 1.20 (1.12–1.29) 1.08 (1.01–1.16)
41st–60th (152–171 mg/dL) 11,467 1690 42,565 397.0 1.13 (1.05–1.21) 1.06 (0.99–1.13)
61st–80th (172–196 mg/dL) 11,903 1466 44,807 327.2 Reference Reference
81st–95th (197–233 mg/dL) 8690 996 33,300 299.1 0.96 (0.88–1.04) 1.03 (0.95–1.11)
96th–100th (> 233 mg/dL) 2922 410 11,228 365.1 1.25 (1.12–1.39) 1.35 (1.21–1.51)

Multivariable-adjusted model was adjusted for age, sex, BMI, use of lipid-lowering agents, presence of CKD, DM, and HTN, smoking status, alcohol consumption, and cancer type.

CKD chronic kidney disease, DM diabetes mellitus, HR hazard ratio, HTN hypertension, NED no evidence of disease, TC total cholesterol, CI confidence interval.