Table 2.

Spearman correlation between inflammatory signaling activation and replication stress markers and relative oncogenes among overall samples and different subtypes.

		γH2AX	pRPA	Cyclin E1 (n)	Cyclin E1 (c)	c-Myc
Overall
pSTAT1	correlation	0.326	0.219	0.295	0.176	0.296
	P value	<0.0001	<0.0001	<0.0001	0.001	<0.0001
pTBK1	correlation	0.127	0.111	0.062	0.066	0.241
	P value	0.018	0.035	0.245	0.216	<0.0001
pnSTING	correlation	0.006	−0.010	0.044	0.049	0.056
	P value	0.914	0.854	0.403	0.359	0.294
ER+/HER2−
pSTAT1	correlation	0.146	0.269	0.173	0.030	0.269
	P value	0.051	<0.001	0.022	0.693	<0.001
pTBK1	correlation	0.171	0.000	−0.097	−0.097	0.287
	P value	0.022	0.997	0.201	0.200	<0.0001
pnSTING	correlation	0.093	−0.012	−0.017	0.050	0.007
	P value	0.219	0.877	0.828	0.51609	0.926
HER2+
pSTAT1	correlation	0.209	0.226	0.022	0.046	0.103
	P value	0.032	0.021	0.823	0.642	0.295
pTBK1	correlation	−0.012	0.276	0.041	−0.035	0.075
	P value	0.904	0.005	0.680	0.727	0.445
pnSTING	correlation	−0.111	0.004	0.112	0.059	−0.008
	P value	0.259	0.971	0.256	0.553	0.932
TNBC
pSTAT1	correlation	0.176	0.213	0.280	−0.180	−0.029
	P value	0.137	0.047	0.012	0.108	0.806
pTBK1	correlation	−0.062	0.126	0.060	0.058	0.159
	P value	0.611	0.257	0.608	0.618	0.188
pnSTING	correlation	−0.151	0.011	−0.151	−0.100	−0.047
	P value	0.207	0.923	0.183	0.379	0.691

P values in bold indicate P < 0.05.