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. 2024 Jan 2;10:1. doi: 10.1038/s41523-023-00609-z

Table 3.

Relation between pSTAT1 versus markers of genomic instability and clinicopathological characteristics among the study cohort.

pSTAT1 Univariate Multivariate
Beta 95% CI P value Beta 95% CI P value
Tumor subtypes ER+/HER2- Ref. Ref.
HER2+ 0.125 2.085–19.001 0.015 0.046 −5.278–12.442 0.427
TNBC 0.420 28.602–46.639 <0.0001 0.134 −2.400–26.212 0.103
Tumor grade I Ref. Ref.
II 0.106 −2.024–19.093 0.113 0.084 −3.607–16.195 0.212
III 0.339 15.832–35.847 <0.0001 0.165 0.769–22.728 0.036
Tumor Stage I Ref.
II −0.036 −11.232–5.566 0.508
III 0.043 −7.333–17.302 0.427
γH2AX 0.369 0.401–0.687 <0.0001 0.221 0.157–0.495 <0.0001
pRPA 0.167 0.053–0.218 0.001 0.151 0.035–0.201 0.006
Cyclin E1(n) 0.264 0.140–0.313 <0.0001 0.067 −0.064–0.180 0.351
Cyclin E1(c) 0.170 0.054–0.218 0.001 −0.089 −0.175–0.039 0.214
c-Myc 0.260 0.172–0.392 <0.0001 0.139 0.020–0.273 0.023

P values in bold indicate P < 0.05.