Table 4.
Univariate and multivariate COX regression analysis of pSTAT1 of breast cancer-specific survival (BCSS) based on clinical parameters and pSTAT1 expression.
| Univariate | Multivariate | ||||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | ||
| Tumor subtypes | ER+/HER2− | Ref. | Ref. | ||||
| HER2+ | 0.997 | 0.368–2.703 | 0.995 | 1.961 | 0.569-6.761 | 0.286 | |
| TNBC | 3.358 | 1.512–7.459 | 0.003 | 4.131 | 1.089–15.676 | 0.037 | |
| Tumor grade | I | Ref. | Ref. | ||||
| II | 1.876 | 0.378–9.313 | 0.442 | 2.090 | 0.391–11.171 | 0.389 | |
| III | 5.117 | 1.2–21.816 | 0.027 | 5.225 | 0.977–27.960 | 0.053 | |
| Stage | I | Ref. | Ref. | ||||
| II | 1.94 | 0.780–4.824 | 0.154 | 3.862 | 1.217–12.256 | 0.022 | |
| III | 6.268 | 2.560–15.347 | <0.001 | 3.846 | 1.256–11.782 | 0.018 | |
| Chemotherapy | No | Ref. | |||||
| Yes | 1.219 | 0.525–2.829 | 0.645 | ||||
| Radiotherapy | No | Ref. | |||||
| Yes | 0.677 | 0.319–1.440 | 0.311 | ||||
| pSTAT1 | Low | 0.328 | 0.145–0.745 | 0.008 | 0.644 | 0.244–1.702 | 0.375 |
| High | Ref. | Ref. | |||||
P values in bold indicate P < 0.05.