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. 2024 Jan 2;7:5. doi: 10.1038/s42003-023-05689-y

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — (a) In all PC models, spikes are generated in the AIS and then propagate actively in the axon and passively in the dendrite, where they undergo a marked decrement and slowdown. Traces show the spontaneous spike discharge in different model compartments. The corresponding PC model morphologies are shown on the side (with the colors indicating the recording site). (b) Spikes taken from the same simulations as in A are overlay for AIS, soma, axon, aspiny, and spiny dendrites. Note that the AIS spike precedes those in any other compartment (same colors as in a).