Table 3.
Somatic CNV calling performance comparison on 13 bladder cancer test samples from Guo et al.31
Tool | DEL Precision | DUP Precision | Overall Precision | DEL Recall | DUP Recall | Overall Recall | DEL F1 Score | DUP F1 Score | Overall F1 Score |
---|---|---|---|---|---|---|---|---|---|
XHMM | 0.235 | 0.962 | 0.698 | 0.012 | 0.028 | 0.020 | 0.023 | 0.054 | 0.038 |
DECoNT-XHMM | 0.193 | 0.950 | 0.572 | 0.010 | 0.023 | 0.017 | 0.019 | 0.045 | 0.033 |
ECOLE | 0.373 | 0.673 | 0.523 | 0.019 | 0.010 | 0.015 | 0.036 | 0.020 | 0.029 |
ECOLEFT−SOMATIC | 0.243 | 0.423 | 0.333 | 0.147 | 0.372 | 0.260 | 0.183 | 0.395 | 0.292 |
CNVnator calls are used as the semi-ground truth to calculate the metrics.