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. 2024 Jan 2;14:114. doi: 10.1038/s41598-023-50277-z

Table 3.

The association between the demographic, clinical and laboratory variables and the MTHFR C677T polymorphisms in stroke patients.

CT
n = 81
CT + TT
n = 92
CC
n = 8
TT
n = 11
Test (p) P1 Test (p) P2
SBP (mmHg) 130 (100–190) 130 (90–190) 135 (120–160) 140 (90–160) F = 0.553 0.577 T = 0.960 0.339
DBP (mmHg) 80 (60–100) 80 (50–100) 80 (70–90) 80 (50–100) F = 0.739 0.48 T = 0.101 0.921
TG (mg/dl) 120 (26–887) 121.5 (26–887) 105.5 (62–231) 131 (98–276) H = 0.632 0.729 U = 400.0 0.684
TC (mg/dl) 16 7 (80–302) 169.5 (80–302) 126 (72–196) 190 (126–253) F = 2.821 0.044 T = 2.017 0.046
HDL-C (mg/dl) 30.9 (28.6–37.8) 36 (25–60) 30.9 (28.6–37.8) 36 (28–50) F = 2.740 0.046 T = 2.225 0.028
LDL-C (mg/dl) 105.6 (30.3–222.4) 108.9 12.4–222.4) 70.6 (31–146) 128.9 (45.2–165.8) H = 4.131 0.127 U = 507.5 0.076
VLDL-C (mg/dl) 105.6 (30.3–222.4) 24.3 (5.2–177.4) 21.1 (12.4–46.2) 128.9 (45.2–165.8) H = 0.632 0.729 U = 400.0 0.684
Gender
 Male 52(64.2%) 58 (63%) 2 (25%) 6 (54.5%) X2 = 4.814 0.092 X2 = 4.438 0.057
 Female 29 (35.8%) 34 (37%) 6 (75%) 5 (45.5%)
Smoking status
 Absent 6(75%) 41 (50.6%) 7 (63.6%) 48 (52.2%) 2.205 0.332 1.544 0.214
 Present 2 (25%) 40 (49.4%) 4 (36.4%) 44 (47.8%)

OR odds ratio, CI confidence interval, P1 comparison between CT, CC and TT, P2 comparison between CT + TT versus CC, F ANOVA, T student t test, U Mann Whitney test, X2 chi square test.