Fig. 5. AKA administration of IL4I1-cKO mice.

a Experimental design of AKA treatment of LPC-induced demyelinated IL4I1-cKO mice. b–d Representative images, and quantification of Iba1⁺ and Iba1⁺iNOS⁺ cells in lesions from PBS or AKAs-treated IL4I1-cKO mice and PBS-treated control mice (n = 2–3 mice, one-way ANOVA). e–g Representative images, and quantification of CD68⁺ and CD68⁺pS6⁺ cells in lesions from PBS or AKAs-treated IL4I1-cKO mice and PBS-treated control mice (n = 2–3 mice, one-way ANOVA). Bars represent the means with SEM. Each point represents an individual value. *P < 0.05, **P < 0.01, ns = not significant.