Table 1.
Demographics and clinical characteristics.
| Characteristic | All | Age-matched cohort | MRI | ||||
|---|---|---|---|---|---|---|---|
| HC (N = 79) | MS (N = 279) | P value | RRMS (N = 81) | PMS (N = 81) | P value | MS Cohort (N = 105) | |
| Samples, n | 156 | 408 | 81 | 81 | 105 | ||
| Age, years, mean (SD) | 42.0 (13.5) | 44.4 (12.2) | 0.17a | 50.2 (8.9) | 52.8 (9.9) | 0.09a | 43.7 (13.0) |
| Female, n (%) | 50 (63%) | 205 (73%) | 0.08b | 65 (80%) | 53 (65%) | 0.03b | 78 (74) |
| Race, n (%) | 0.01b | 0.21b | - | ||||
| White | 59 (75%) | 237 (85%) | 73 (90%) | 66 (81%) | 90 (86) | ||
| African American | 10 (13%) | 32 (11%) | 7 (8.6%) | 11 (14%) | 10 (9.5) | ||
| Other | 10 (13%) | 10 (3.6%) | 1 (1.2%) | 4 (4.9%) | 5 (4.8) | ||
| PMS, n (%) | - | 94 (34%) | 26 (25) | ||||
| Time from blood draw, months, median (IQR) | - | - | - | - | 6.0 (1.9–8.3) | ||
ap values derived from two-sample t test.
bp values derived from chi-squared test.
Statistically significant values (<0.05) are bolded.
HC healthy controls, IQR inter-quantile range, MS multiple sclerosis, PMS progressive multiple sclerosis, RRMS relapsing-remitting multiple sclerosis, SD standard deviation.