Table 1.
Characteristics of the participants according to their LEPR genotypes
| Parameter | Total | rs1173100 | rs1137101 | rs790419 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| G/G | G/A | A/A | G/G | G/A | T/T | T/C | ||||
| n | 65 | 17 | 37 | 11 | 52 | 13 | 58 | 7 | ||
| Age (yr) | 35.2 ± 8.1 | 36.6 ± 8.6 | 34.0 ± 7.5 | 36.7 ± 9.3 | 35.6 ± 8.2 | 33.3 ± 7.8 | 35.0 ± 8.2 | 36.7 ± 7.8 | ||
| Sex [male:female(n)] | 7:58 | 1:16 | 6:31 | 0:11 | 6:46 | 1:12 | 6:52 | 1:06 | ||
| Body Mass Index (kg/m2) | 21.4 ± 1.8 | 21.4 ± 2.0 | 21.6 ± 1.7 | 20.7 ± 1.7 | 21.4 ± 1.8 | 21.0 ± 1.7 | 21.2 ± 1.7 | 22.6 ± 2.2 | ||
| Leptin (pg/mL) | 7989.1 ± 6687.4 | 7074.3 ± 2697.8 | 8959.5 ± 8211.5 | 6227.1 ± 5086.0 | 8415.0 ± 7332.5 | 6318.3 ± 2639.8 | 7804.1 ± 6727.5 | 9495.2 ± 6647.1 | ||
| Triglyceride (mg/dL) | 101.4 ± 75.7 | 92.8 ± 46.2 | 109.8 ± 89.1 | 86.6 ± 63.1 | 102.7 ± 82.6 | 96.2 ± 38.6 | 98.3 ± 72.4 | 127.4 ± 102.0 | ||
| HDL-C (mg/dL) | 72.9 ± 18.1 | 74.8 ± 16.1 | 76.6 ± 18.8 | 67.8 ± 19.5 | 73.5 ± 19.0 | 70.6 ± 14.0 | 74.2 ± 17.7 | 62.9 ± 19.6 | ||
| LDL-C (mg/dL) | 102.9 ± 27.8 | 93.1 ± 21.8 | 105.5 ± 30.3 | 109.5 ± 25.5 | 104.4 ± 28.8 | 96.9 ± 23.6 | 102.3 ± 26.6 | 108.3 ± 38.6 | ||
HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Data presented as mean ± standard deviation.