Table 5.
Mean concentrations (nmol/L) with 2.5 and 97.5 percentiles for androgens, SHBG, and 17-OHP in males and females. For progesterone in premenopausal females (which was not normally distributed) median, minimum and maximum concentrations (nmol/L) are shown. For estradiol in all groups, and for progesterone in males and postmenopausal females, the method has insufficient sensitivity. Therefore, only the maximum value observed is listed.
Males | Females | ||||||
---|---|---|---|---|---|---|---|
30–39 years (n = 34) | 40–49 years (n = 60) | 50–59 years (n = 53) | 60–90 years (n = 143) | Males (n = 290) | Premenopausal (n = 80) | Postmenopausal (n = 149) | |
DHEAS | 5745 (2782–11864) | 5108 (1230–8987) | 3942 (986–8867) | 1831 (502–6678) | 3468 (1023–7362) | 1340 (277–6488) | |
DHEA | 18.39 (6.53–51.78) | 13.35 (5.95–29.98) | 10.58 (4.51–24.83) | 5.40 (0.85–13.86) | 13.61 (6.37–29.10) | 5.53 (1.14–26.86) | |
Androstenedione | 3.63 (1.67–7.86) | 3.49 (1.80–6.79) | 3.48 (1.90–6.37) | 2.01 (0.93–4.38) | 3.69 (1.81–7.54) | 1.59 (0.62–4.06) | |
17-OHP | 3.13 (1.02–5.24) | 2.92 (1.37–6.23) | 2.23 (0.86–5.80) | 2.14 (0.56–4.76) | 1.58 (0.29–8.73) | 0.54 (0.13–2.16) | |
Testosterone | 17.44 (9.02–33.70) | 16.40 (8.95–30.06) | 13.97 (6.34–30.76) | 16.64 (8.18–28.07) | 0.81 (0.37–1.79) | 0.75 (0.25–2.23) | |
SHBG | 43.69 (8.13–79.25) | 41.18 (18.38–92.23) | 48.66 (14.56–102.71) | 60.82 (29.38–125.90) | 73.13 (32.94–162.36) | 75.22 (32.00–176.78) | |
FAI | 46.20 (18.31–74.08) | 39.83 (19.59–80.99) | 30.34 (14.69–62.65) | 27.29 (13.27–46.32) | 1.11 (0.40–3.08) | 1.00 (0.27–3.74) | |
Estradiol | <0.23 | <3.64 | <0.48 | ||||
Progesterone | <0.56 | 11.912 (0.071–72.1) | <0.36 |
For progesterone in premenopausal females, median and minimum–maximum values (nmol/L) are given.
17-OHP, 17-hydroxyprogesterone; DHEA, dehydroepiandrosterone; DHEAS, dehydroepiandrosterone sulfate; FAI, free androgen index (given without unit).