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. 2023 Dec 11;13(1):e230225. doi: 10.1530/EC-23-0225

Table 5.

Mean concentrations (nmol/L) with 2.5 and 97.5 percentiles for androgens, SHBG, and 17-OHP in males and females. For progesterone in premenopausal females (which was not normally distributed) median, minimum and maximum concentrations (nmol/L) are shown. For estradiol in all groups, and for progesterone in males and postmenopausal females, the method has insufficient sensitivity. Therefore, only the maximum value observed is listed.

Males Females
30–39 years (n = 34) 40–49 years (n = 60) 50–59 years (n = 53) 60–90 years (n = 143) Males (n = 290) Premenopausal (n = 80) Postmenopausal (n = 149)
DHEAS 5745 (2782–11864) 5108 (1230–8987) 3942 (986–8867) 1831 (502–6678) 3468 (1023–7362) 1340 (277–6488)
DHEA 18.39 (6.53–51.78) 13.35 (5.95–29.98) 10.58 (4.51–24.83) 5.40 (0.85–13.86) 13.61 (6.37–29.10) 5.53 (1.14–26.86)
Androstenedione 3.63 (1.67–7.86) 3.49 (1.80–6.79) 3.48 (1.90–6.37) 2.01 (0.93–4.38) 3.69 (1.81–7.54) 1.59 (0.62–4.06)
17-OHP 3.13 (1.02–5.24) 2.92 (1.37–6.23) 2.23 (0.86–5.80) 2.14 (0.56–4.76) 1.58 (0.29–8.73) 0.54 (0.13–2.16)
Testosterone 17.44 (9.02–33.70) 16.40 (8.95–30.06) 13.97 (6.34–30.76) 16.64 (8.18–28.07) 0.81 (0.37–1.79) 0.75 (0.25–2.23)
SHBG 43.69 (8.13–79.25) 41.18 (18.38–92.23) 48.66 (14.56–102.71) 60.82 (29.38–125.90) 73.13 (32.94–162.36) 75.22 (32.00–176.78)
FAI 46.20 (18.31–74.08) 39.83 (19.59–80.99) 30.34 (14.69–62.65) 27.29 (13.27–46.32) 1.11 (0.40–3.08) 1.00 (0.27–3.74)
Estradiol <0.23 <3.64 <0.48
Progesterone <0.56 11.912 (0.071–72.1) <0.36

For progesterone in premenopausal females, median and minimum–maximum values (nmol/L) are given.

17-OHP, 17-hydroxyprogesterone; DHEA, dehydroepiandrosterone; DHEAS, dehydroepiandrosterone sulfate; FAI, free androgen index (given without unit).