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Table 1.

Baseline clinicopathological characteristics for all neuroendocrine tumors in the training set and testing set.

Variables All patients (n = 29,285) (%) Training set (n = 20,499) (%) Validation set (n = 8786) (%) P
Sex 0.671
 Male 13,798 (47.1) 9675 (47.2) 4123 (46.9)
 Female 15,487 (52.9) 10,824 (52.8) 4663 (53.1)
Age, years 0.699
 <30 1476 (5.0) 1035 (5.1) 441 (5.0)
 30–59 13,696 (46.8) 9554 (46.6) 4142 (47.2)
 ≥60 14,113 (48.2) 9910 (48.3) 4203 (47.8)
Race 0.053
 White 23,046 (78.7) 16,114 (78.6) 6932 (78.9)
 Black 4112 (14.0) 2848 (13.9) 1264 (14.4)
 AI/ANa 167 (0.6) 114 (0.6) 53 (0.6)
 A/PIb 1960 (6.7) 1423 (6.9) 537 (6.1)
Year of diagnosis 0.379
 2000–2004 2435 (8.3) 1739 (8.5) 696 (7.9)
 2005–2009 4527 (15.5) 3178 (15.5) 1349 (15.4)
 2010–2014 11,414 (39.0) 7950 (38.8) 3464 (39.4)
 2015–2018 10,909 (37.2) 7632 (37.2) 3277 (37.3)
Grade 0.657
 I 19,064 (65.1) 13,314 (64.9) 5750 (65.4)
 II 4853 (16.6) 3389 (16.5) 1464 (16.7)
 III 4017 (13.7) 2841 (13.9) 1176 (13.4)
 IV 1351 (4.6) 955 (4.7) 396 (4.5)
Stage 0.693
 Localized 15,604 (53.3) 10,889 (53.1) 4715 (53.7)
 Regional 7039 (24.0) 4944 (24.1) 2095 (23.8)
 Distant 6642 (22.7) 4666 (22.8) 1976 (22.5)
Site 0.555
 Lung 6879 (23.5) 4785 (23.4) 2094 (23.8)
 Appendix 3003 (10.3) 2109 (10.3) 894 (10.2)
 Cecum 918 (3.1) 661 (3.2) 257 (2.9)
 Colon 1009 (3.5) 722 (3.5) 287 (3.3)
 Pancreas 4370 (14.9) 3093 (15.1) 1277 (14.5)
 Rectum 4793 (16.4) 3327 (16.2) 1466 (16.7)
 Small intestine 6337 (21.6) 4426 (21.6) 1911 (21.8)
 Stomach 1976 (6.7) 1376 (6.7) 600 (6.8)

aAI/AN: American Indian and Alaska Native; bA/PI: Asian and Pacific Islander.