Table 1.
Baseline clinicopathological characteristics for all neuroendocrine tumors in the training set and testing set.
| Variables | All patients (n = 29,285) (%) | Training set (n = 20,499) (%) | Validation set (n = 8786) (%) | P |
|---|---|---|---|---|
| Sex | 0.671 | |||
| Male | 13,798 (47.1) | 9675 (47.2) | 4123 (46.9) | |
| Female | 15,487 (52.9) | 10,824 (52.8) | 4663 (53.1) | |
| Age, years | 0.699 | |||
| <30 | 1476 (5.0) | 1035 (5.1) | 441 (5.0) | |
| 30–59 | 13,696 (46.8) | 9554 (46.6) | 4142 (47.2) | |
| ≥60 | 14,113 (48.2) | 9910 (48.3) | 4203 (47.8) | |
| Race | 0.053 | |||
| White | 23,046 (78.7) | 16,114 (78.6) | 6932 (78.9) | |
| Black | 4112 (14.0) | 2848 (13.9) | 1264 (14.4) | |
| AI/ANa | 167 (0.6) | 114 (0.6) | 53 (0.6) | |
| A/PIb | 1960 (6.7) | 1423 (6.9) | 537 (6.1) | |
| Year of diagnosis | 0.379 | |||
| 2000–2004 | 2435 (8.3) | 1739 (8.5) | 696 (7.9) | |
| 2005–2009 | 4527 (15.5) | 3178 (15.5) | 1349 (15.4) | |
| 2010–2014 | 11,414 (39.0) | 7950 (38.8) | 3464 (39.4) | |
| 2015–2018 | 10,909 (37.2) | 7632 (37.2) | 3277 (37.3) | |
| Grade | 0.657 | |||
| I | 19,064 (65.1) | 13,314 (64.9) | 5750 (65.4) | |
| II | 4853 (16.6) | 3389 (16.5) | 1464 (16.7) | |
| III | 4017 (13.7) | 2841 (13.9) | 1176 (13.4) | |
| IV | 1351 (4.6) | 955 (4.7) | 396 (4.5) | |
| Stage | 0.693 | |||
| Localized | 15,604 (53.3) | 10,889 (53.1) | 4715 (53.7) | |
| Regional | 7039 (24.0) | 4944 (24.1) | 2095 (23.8) | |
| Distant | 6642 (22.7) | 4666 (22.8) | 1976 (22.5) | |
| Site | 0.555 | |||
| Lung | 6879 (23.5) | 4785 (23.4) | 2094 (23.8) | |
| Appendix | 3003 (10.3) | 2109 (10.3) | 894 (10.2) | |
| Cecum | 918 (3.1) | 661 (3.2) | 257 (2.9) | |
| Colon | 1009 (3.5) | 722 (3.5) | 287 (3.3) | |
| Pancreas | 4370 (14.9) | 3093 (15.1) | 1277 (14.5) | |
| Rectum | 4793 (16.4) | 3327 (16.2) | 1466 (16.7) | |
| Small intestine | 6337 (21.6) | 4426 (21.6) | 1911 (21.8) | |
| Stomach | 1976 (6.7) | 1376 (6.7) | 600 (6.8) |
aAI/AN: American Indian and Alaska Native; bA/PI: Asian and Pacific Islander.
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