Table 1.

Demographic, clinical, and histopathological characteristics of the 104 patients with adrenocortical carcinoma evaluated for PLK1 immunohistochemistry.

Parameter	Value
Demographic and clinical parameters
Sex (M/F)	45/59
Age – years (median, range)	49 (18–87)
Initial ENSAT tumour stage (n)
1–2	56
3	27
4	22
Pre-operative steroid secretion (n)
Cortisol	23
Other single steroids (androgens, mineralocorticoids, or oestrogens)	9
Mixed steroids	21
Inactive	25
Histopathological parameters
Ki67 index – % (median, range)	15 (1–90)
Resection status (n)
R0	73
RX	16
R1	5
R2	8
Unknown	3
Tumour localisation (n)
Primary surgery	86
Local recurrence	8
Distant metastasis	10
Post-surgical pharmacological treatment
Adjuvant mitotane (n)	38
Palliative mitotane (n)	38
Cytotoxic chemotherapy	63

ENSAT, European Network for the Study of Adrenal Tumors; F, female; M, male; n, number of patients; R0, complete resection; R1, microscopic incomplete resection; R2, macroscopic incomplete resection; RX, uncertain resection.