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. 2023 May 26;15(1):6–20. doi: 10.1093/procel/pwad032

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©The Author(s) 2023. Published by Oxford University Press on behalf of Higher Education Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Research history of eccDNAs in gynecologic tumors and reproduction. Notable studies on eccDNAs in gynecologic oncology are listed on the upper side of the timeline. Milestone findings on eccDNAs in reproduction are shown below the timeline. The discovery, slow development, and rapid development research stages are separated by rectangular boxes.