Anti-cancer activity results.
| Compounds | Cell viability (%) ±SD | Compounds | Cell viability (%) ±SD | ||||
|---|---|---|---|---|---|---|---|
| 50 μM | 25 μM | 10 μM | 50 μM | 25 μM | 10 μM | ||
| 22 | 85.37 ± 4.16 | 87.49 ± 6.74 | 92.40 ± 5.38 | 36 | 41.20 ± 1.26 | 46.10 ± 3.32 | 70.37 ± 5.36 |
| 23 | 34.32 ± 5.29 | 49.03 ± 9.19 | 65.14 ± 8.53 | 37 | 78.74 ± 2.56 | 80.51 ± 8.96 | 85.23 ± 3.50 |
| 24 | 98.54 ± 2.89 | 100.13 ± 8.93 | 100.25 ± 8.01 | 38 | 67.70 ± 10.82 | 89.59 ± 9.91 | 92.04 ± 8.31 |
| 25 | 86.22 ± 9.22 | 93.24 ± 1.96 | 98.58 ± 2.25 | 39 | 97.50 ± 1.88 | 98.25 ± 0.34 | 101.28 ± 9.67 |
| 26 | 54.56 ± 5.61 | 59.98 ± 8.47 | 76.61 ± 9.76 | 40 | 91.74 ± 9.12 | 92.81 ± 7.09 | 99.05 ± 7.70 |
| 27 | 74.75 ± 7.02 | 89.80 ± 8.75 | 93.24 ± 8.51 | 41 | 44.18 ± 4.11 | 54.28 ± 6.12 | 66.70 ± 8.21 |
| 28 | 69.46 ± 17.69 | 99.07 ± 3.51 | 102.13 ± 8.51 | 42 | 75.55 ± 8.45 | 78.52 ± 6.58 | 81.32 ± 7.65 |
| 29 | 88.43 ± 7.36 | 81.48 ± 2.58 | 89.10 ± 4.09 | 43 | 71.36 ± 10.49 | 95.16 ± 10.62 | 99.50 ± 10.20 |
| 30 | 42.82 ± 5.04 | 55.17 ± 7.06 | 86.58 ± 3.36 | 44 | 89.57 ± 6.27 | 90.13 ± 6.77 | 98.41 ± 3.62 |
| 31 | 78.81 ± 10.40 | 88.47 ± 6.73 | 81.68 ± 8.36 | 45 | 86.98 ± 1.10 | 91.06 ± 6.00 | 96.84 ± 5.85 |
| 32 | 72.48 ± 6.24 | 86.20 ± 8.63 | 92.51 ± 9.39 | 46 | 83.54 ± 7.27 | 75.49 ± 4.44 | 80.63 ± 4.70 |
| 33 | 46.98 ± 4.91 | 63.28 ± 6.32 | 66.70 ± 8.23 | 47 | 81.53 ± 5.45 | 89.82 ± 2.22 | 101.77 ± 9.28 |
| 34 | 73.04 ± 2.62 | 76.76 ± 2.43 | 78.46 ± 2.43 | 48 | 92.89 ± 9.08 | 93.31 ± 3.60 | 96.45 ± 4.91 |
| 35 | 75.33 ± 6.17 | 78.62 ± 10.05 | 82.40 ± 9.97 | YM155 (20 nM) | 23.39 ± 3.13 | ||
| Menadione (20 μM) | 23.76 ± 5.70 | ||||||