Table 4.

Effect of Different Variables on Overall Survival (OS) of AML Patients

	Total No.		No. of Events		Cumulative survival at 2year (%)		Median survival time (months)		P value
Whole group	111		83		0.198		2.07		-
Gender
Female	52		44		0.056		1.55		0.014
Male	59		39		0.313		3.45
Age (years)
≤40	57		41		0.183		4.14		0.216
>40	54		42		0.2		1.41
TLC (n=109)
≤100 X109/L	79		60		0.185		2.96		0.487
>100 X109/L	30		23		0.214		1.41
Hemoglobin (n=109)
≤10 g/dl	104		80		0.176		2		0.34
>10 g/dl	5		3		0.400		12.2
Platelets (n=109)
≤100 X 109/L	87		66		0.185		2		0.745
>100 X 109/L	22		17		0.205		3.42
PB blasts%
≤ 50	31		23		0.148		3.55		0.71
> 50	80		60		0.221		2
BMA blast %
≤ 50	18		12		0.216		8.72		0.347
> 50	93		71		0.202		2
BMA cellularity
Hypercellular	95		70		0.204		2.07		0.92
Hypocellular	7		6				10.76
Normocellular	9		7		0.222		1.35
Lymphadenopathy (n=105)
No	62		44		0.245		2.07		0.618
Yes	43		34		0.142		2.34
Organomegally (n=105)
No	68		48		0.226		3.55		0.167
Yes	37		30		0.17		2
FAB classification (n=105)
M1&M2	54		40		0.219		1.55		0.441
M4&M5	51		37		0.219		3.68
CD34 (n=110)
No	53		38		0.24		2.43		0.674
Yes	57		44		0.162		2.07
DR (n=110)
No	29		23		0.162		2		0.656
Yes	81		59		0.228		2.43
CD7 (n=110)
No	91		69		0.204		2.07		0.387
Yes	19		13		0.167		4.14
NPM (n=100)
Mutant	14		5		0.595				0.005
Wild	86		70		0.133		1.61
	Total No.		No. of Events		Cumulative survival at 2year (%)		Median survival time (months)		P value
FLT3 ITD
Mutant	38		32		0.118		1.55		0.035
Wild	73		51		0.242		3.42
Combined FLT3&NPM with ITD ratio (n=100)
Favourable (a)		11		3		0.682		NA		0.002
Unfavorable (b)		13		12		NA		1.32
Intermediate (b)		76		60		0.153		1.74
ITD Ratio (n=27)
≤ 0.525		13		9		0.308		6.71		0.114
>0.525		14		12		NR		1.32
TKD (n=110)
Mutant		5		3		0.3		7.89		0.489
Wild		105		79		0.194		2.07
DNMTA (n=110)
Mutant		11		8		0.227		2.96		0.755
Wild		99		74		0.198		2
IDH1&IDH2
Either IDH1 and or IDH2 mutant		10		8		0.2		0.82		0.37
Both wild		101		75		0.197		2.43
TET2
Mutant		58		43		0.189		2.83		0.645
Wild		53		40		0.207		1.55
CR (n=98)
No		47		46		0.021		0.79		<0.001
Yes		51		24		0.413		14.44