Table 5.
The top 10 molecules, pathological processes and diseases associated with CAFs.
| Molecules | Count | Pathological processes | Count | Diseases | Count |
|---|---|---|---|---|---|
| TGF-β | 853 | Growth | 1127 | Breast Cancer | 1144 |
| Fibroblast Activation Protein | 254 | Metastasis | 947 | Colorectal Cancer | 682 |
| NF-κB | 237 | Progression | 733 | Pancreatic Cancer | 502 |
| Endothelial Growth-Factor | 229 | Epithelial Mesenchymal Transition | 654 | Lung Cancer | 384 |
| Interleukin-6 | 151 | Invasion | 590 | Hepatocellular Carcinoma | 309 |
| Collagen | 134 | Activation | 506 | Prostate Cancer | 292 |
| α-SMA | 134 | Angiogenesis | 504 | Gastric Cancer | 227 |
| Caveolin-1 | 108 | Proliferation | 370 | Head And Neck Cancer | 207 |
| Podoplanin | 103 | Migration | 355 | Ovarian Cancer | 168 |
| Matrix Metalloproteinases | 102 | Inflammation | 234 | Cholangiocarcinoma | 102 |