TABLE 2.

The MR results of the relationship between PUFAs and iNPH.

Exposures	Method	SNP	Beta	SE	OR	OR_lci95	OR_uci95	p
ω-3 PUFAs	MR Egger	46	−0.293	0.159	0.746	0.546	1.020	0.073
	Weighted median	46	−0.337	0.149	0.714	0.533	0.957	0.024
	IVW	46	−0.290	0.115	0.748	0.597	0.937	0.012
	Simple mode	46	0.007	0.426	1.007	0.437	2.321	0.986
	Weighted mode	46	−0.323	0.149	0.724	0.541	0.969	0.035
DHA	MR Egger	41	−0.521	0.209	0.594	0.394	0.895	0.017
	Weighted median	41	−0.396	0.175	0.673	0.478	0.949	0.024
	IVW	41	−0.343	0.146	0.709	0.532	0.945	0.019
	Simple mode	41	−0.351	0.513	0.704	0.257	1.926	0.498
	Weighted mode	41	−0.409	0.166	0.664	0.480	0.919	0.018
DPA	MR Egger	3	−1.221	2.907	0.295	0.001	87.834	0.747
	Weighted median	3	−0.959	0.651	0.383	0.107	1.374	0.141
	IVW	3	−0.961	0.969	0.382	0.057	2.555	0.321
	Simple mode	3	−2.057	1.155	0.128	0.013	1.230	0.217
	Weighted mode	3	−1.284	0.708	0.277	0.069	1.110	0.212
EPA	MR Egger	4	0.187	0.274	1.206	0.704	2.064	0.565
	Weighted median	4	0.005	0.200	1.005	0.679	1.486	0.982
	IVW	4	−0.120	0.174	0.887	0.631	1.247	0.490
	Simple mode	4	−0.021	0.255	0.979	0.594	1.613	0.940
	Weighted mode	4	−0.007	0.216	0.993	0.651	1.516	0.977
ALA	Wald ratio	1	−7.260	3.265	0.001	1.17E-06	0.423	0.026
ω-6 PUFAs	MR Egger	50	0.001	0.383	1.001	0.473	2.120	0.997
	Weighted median	50	0.018	0.277	1.018	0.592	1.752	0.948
	IVW	50	−0.067	0.191	0.935	0.644	1.360	0.727
	Simple mode	50	0.236	0.531	1.267	0.448	3.584	0.658
	Weighted mode	50	0.054	0.403	1.055	0.479	2.327	0.894
LA	MR Egger	43	0.514	0.412	1.672	0.746	3.748	0.219
	Weighted median	43	0.090	0.287	1.094	0.624	1.919	0.754
	IVW	43	0.082	0.197	1.086	0.738	1.597	0.675
	Simple mode	43	0.183	0.533	1.201	0.423	3.412	0.733
	Weighted mode	43	0.141	0.406	1.151	0.519	2.552	0.731
AA	MR Egger	93	0.003	0.004	1.003	0.995	1.011	0.465
	Weighted median	93	−0.004	0.005	0.996	0.987	1.005	0.392
	IVW	93	0.002	0.003	1.002	0.996	1.008	0.461
	Simple mode	93	−0.006	0.009	0.994	0.976	1.012	0.518
	Weighted mode	93	0.002	0.004	1.002	0.995	1.009	0.504