Table 2.
Univariate logistic regression analysis of risk factors for moderate-severe ARDS
| Variables | OR (95% CI) | P value | Variables | OR (95% CI) | P value |
|---|---|---|---|---|---|
| Age (years) | 0.98 (0.97–0.99) | 0.005 | Chronic renal | 1.18 (0.38–3.71) | 0.773 |
| Gender (male) | 1.00 (0.64–1.56) | 0.985 | Diabetes | 0.95 (0.56–1.59) | 0.836 |
| BMI (kg/m2) | 1.03 (1.00–1.07) | 0.071 | Respiratory mechanics parameters | ||
| PBW (kg) | 1.00 (0.98–1.03) | 0.653 | VT (ml/kg PBW) | 1.02 (0.89–1.17) | 0.739 |
| SOFA score | 1.11 (1.04–1.18) | 0.003 | PEEP (cmH2O) | 1.31 (1.21–1.43) | < 0.001 |
| SAPS II | 1.00 (0.98–1.01) | 0.790 | Pplat (cmH2O) | 1.15 (1.1–1.21) | < 0.001 |
| Causes of ARDS | ΔP (cmH2O) | 1.04 (0.99–1.10) | 0.096 | ||
| Sepsis | 1.18 (0.74–1.89) | 0.491 | RR (bpm) | 1.11 (1.06–1.17) | < 0.001 |
| Respiratory disease | 1.07 (0.67–1.72) | 0.769 | Cst (ml/cmH2O) | 0.99 (0.98–1.01) | 0.445 |
| Trauma | 3.4 (0.78–14.9) | 0.105 | MP (J/min) | 1.15 (1.11–1.20) | < 0.001 |
| Others | 0.62 (0.34–1.14) | 0.125 | EP (J/min) | 1.21 (1.15–1.28) | < 0.001 |
| Comorbidities | FiO2 (%) | 1.06 (1.04–1.08) | < 0.001 | ||
| Coronary artery | 0.66 (0.35–1.25) | 0.205 | Physiological variables in the first 24 h | ||
| COPD | 1.48 (0.54–4.04) | 0.446 | PH | 0.21 (0.03–1.64) | 0.135 |
| Chronic liver | 0.54 (0.09–3.26) | 0.500 | PCO2 (mmHg) | 1.04 (1.02–1.06) | < 0.001 |
ARDS acute respiratory distresssyndrome, BMI body mass index, PBW predicted body weight, SOFA sequential organ failure assessment, SAPS II simplified acute physiology score II, COPD chronic obstructive pulmonary disease, PCO2 partial pressure of carbon dioxide, VT tidal volume, PEEP positive end expiratory pressure, Pplat plateau pressure, ΔP driving pressure, RR respiratory rate, Cst static lung compliance, MP mechanical power, EP elastic power, FiO2 inspired oxygen fraction