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. 2024 Jan 3;19:1. doi: 10.1186/s13011-023-00585-4

Table 1.

Participant characteristics grouped by patient-reported dose satisfaction (N = participant-observations), with significant p-values from unadjusted generalized estimating equations

Characteristic Patient-reported Dose Satisfaction Observations
Overall N = 545a,d Satisfied with Dose N = 423a,d Wants Higher Dose N = 122a,d
Ageb 45.30 (8.91) 45.86 (8.69) 43.37 (9.43)
Genderb
Female 155 (28%) 110 (26%) 45 (37%)
Male 390 (72%) 313 (74%) 77 (63%)
First Nations, Métis, or Inuitb
No 385 (71%) 311 (74%) 74 (61%)
Yes* 160 (29%) 112 (26%) 48 (39%)
Educationb
Less than high school 230 (42%) 172 (41%) 58 (48%)
High School 138 (25%) 103 (24%) 35 (29%)
At least some post-secondary 177 (32%) 148 (35%) 29 (24%)
EQ5D-CAN Scorec 0.79, (0.21) 0.80, (0.21) 0.76, (0.21)
OTI Total Health Score (without gynecological subscale)** c 46.88 (25.98) 44.51 (26.36) 54.96 (22.97)
Ever Attempted Suicideb
No 398 (74%) 327 (78%) 71 (59%)
Yes* 142 (26%) 92 (22%) 50 (41%)
Age First Injected Any Drug* b 23.17 (8.06) 23.68 (8.18) 21.40 (7.38)
Days with heroin use in past month* c 4.35 (8.25) 3.76 (7.62) 6.38 (9.90)
Number of days (out of past 30) patient smoked crack cocaine c 5.14 (10.28) 5.00 (10.29) 5.63 (10.29)
FTND c
Non-Smoker 66 (12%) 63 (15%) 3 (2.5%)
Smoker** 478 (88%) 360 (85%) 118 (98%)
Whether patients were troubled to any extent by any drug problems3
No 257 (47%) 218 (52%) 39 (32%)
Yes** 288 (53%) 205 (48%) 83 (68%)
MAP Psychological Health Score** c 8.49 (7.37) 7.68 (6.95) 11.29 (8.12)
Average Daily Dose Prescribedc 562.59 (261.58) 555.93 (257.78) 585.91 (274.28)
Patient's rating of doctor involving them in decisions as much as they wantedc
Less Than Excellent 275 (52%) 199 (48%) 76 (65%)
Excellent** 254 (48%) 213 (52%) 41 (35%)
Drug Liking VAS*** c 74.22 (24.17) 78.08 (21.08) 61.02 (29.05)

Values are bolded if there is a significant (p < 0.05) difference in means between dose-satisfaction groups (for continuous variables) or significant difference in distribution of dose-satisfaction status between one or more levels of a categorical variable and the (not bolded) reference level

Abbreviations: EQ5D-CAN Canadian version of the EuroQol 5 Dimension descriptive system for health-related quality of life, OTI Opiate Treatment Index, FTND Fagerström Test of Nicotine Dependence, MAP Maudsley Addiction Profile, VAS Visual Assessment Scale

*p < 0.05

**p < 0.01

***p < 0.001

n (%); mean (SD)

Variable collected at SALOME baseline

Variable reflects prior 30 days at the time of RUTH study visit

The N here is observations and each participant has up to 5 observations represented, therefore, some participants have observations) represented in both -groups