Table 2.
Final multivariate generalized estimating equation model (from stepwise model building and comparison process), including adjusted odds ratios of iOAT clients’ likelihood of reporting dissatisfaction with their dose, shown next to unadjusted odds ratios
| Block/Step | Variable (and Variable Level) | Bivariate OR (95% CI) | Multivariate AOR (95% CI) | |
|---|---|---|---|---|
| 1. Socio-demographics | Agea | 0.97 (0.94, 1.01) | 0.996 (0.96, 1.03) | |
| Gender (self-identified) | Womanb | — | — | |
| Man | 0.61 (0.32, 1.16) | 0.818 (0.40, 1.66) | ||
| First Nations, Métis, or Inuit | Nob | — | — | |
| Yes | 1.89 (1.00, 3.56) | 1.38 (0.67, 2.85) | ||
| Education | Some High School or lessb | — | — | |
| High School Diploma | 1.10 (0.53, 2.27) | 1.51 (0.71, 3.22) | ||
| ≥ Some post-secondary | 0.62 (0.31, 1.27) | 0.90 (0.43, 1.87) | ||
| 2. Physical Health | Opiate Treatment Index—Health Section Total Scorec | 1.01 (1.00, 1.02) | 1.01 (0.99, 1.02) | |
| 3. Mental Health | Ever attempted suicide | Nob | — | — |
| Yes | 2.29 (1.20, 4.35) | 1.39 (0.69, 2.81) | ||
| MAP Psychological Score | 1.04 (1.01, 1.08) | 1.01 (0.98, 1.04) | ||
| 4. Quality of Life | EQ5D-CAN Score | 0.41 (0.11, 1.58) | 1.00 (0.22, 4.44) | |
| 5. Substance Use and Treatment | Average Daily Prescribed iOAT dosed | 1.00 (1.00, 1.00) | 1.00 (1.00, 1.00) | |
| Days with heroin use in past month | 1.02 (1.00, 1.05) | 1.00 (0.97, 1.04) | ||
| Days with crack cocaine use in past month | 0.99 (0.96, 1.02) | 1.01 (0.99, 1.04) | ||
| FTND: Current smoker | Non-smokerb | — | — | |
| Smoker | 4.48 (1.66, 12.1) | 1.17 (1.06, 1.30) | ||
| How troubled client reports feeling about problems associated with criminalized drug use | Untroubledb | — | — | |
| Troubled | 2.21 (1.21, 4.01) | 2.06 (1.12, 3.79) | ||
| 6. Shared Decision Making | Client rating of doctor involving them in decisions as much as the client wants | Less than excellentb | — | — |
| Excellent | 0.65 (0.47, 0.88) | 0.81 (0.61, 1.08) | ||
| 7. Drug Liking | Visual Assessment Scale of "Liking the (prescribed) Drug" | 0.98 (0.97, 0.99) | 0.98 (0.97, 0.99) | |
Values are bolded if there is a significant (p < 0.05) difference in means between dose-satisfaction groups (for continuous variables) or significant difference in distribution of dose-satisfaction status between one or more levels of a categorical variable and the (not bolded) reference level
Abbreviations: EQ5D-CAN Canadian version of the EuroQol 5 Dimension descriptive system for health-related quality of life, OTI Opiate Treatment Index, FTND Fagerström Test of Nicotine Dependence, MAP Maudsley Addiction Profile, VAS Visual Assessment Scale
a per 1 year increase
b reference group for both OR and AOR
c (minus Gynecological subscale)
d per 1 mg increase in diacetylmorphine-equivalent-mg