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Functions of m6A ‘erasers’ in liver cancer
| Regulator | Effect on m6A modification | Expression change | (Refs.) |
|---|---|---|---|
| FTO | Removes m6A and m6Am modification, regulates pre-mRNA alternative splicing | Up/down | [45, 46] |
| ALKBH5 | Removes m6A modification, regulate mRNA processing, metabolism and export | Up/down | [49, 50] |
m6A, N6-methyladenosine; FTO, fat mass and obesity-associated protein; ALKBH5, AlkB homolog 5
