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. 2024 Jan 3;19:6. doi: 10.1186/s13023-023-03010-y

Table 2.

Clinical measurement results at baseline and after 4 weeks and 12 weeks of ESWT

RETT measurements CP measurements Comparison of two groups
Variables
(Mean ± SEM)
1
(Baseline)
2
(4 weeks)
3
(12 weeks)
pa 1
(Baseline)
2
(4 weeks)
3
(12 weeks)
pa pb pc
MAS of lower extremity flexor
4.00 ± 0.26 3.50 ± 0.43 3.33 ± 0.49 0.061 2.20 ± 0.30§ 1.63 ± 0.31 1.50 ± 0.28§ 0.011* 0.003** 0.930
Ankle PROM (º)
57.08 ± 3.68 58.33 ± 3.07 58.33 ± 3.07 0.135 47.50 ± 3.88 55.00 ± 2.20 55.50 ± 2.07 0.002** 0.177 0.020*
GMFM-88 Variables Score (%)
Lying and Rolling 68.30 ± 11.63 68.63 ± 11.49 68.95 ± 11.36 0.368 66.93 ± 8.94 67.45 ± 8.83 68.24 ± 8.70 0.305 0.936 0.586
Sitting 53.33 ± 11.46 53.33 ± 11.46 53.33 ± 11.46 1.000 46.33 ± 10.81 49.44 ± 10.76 49.00 ± 10.71 0.079 0.410 0.091
Crawling and Kneeling 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 1.000 29.21 ± 11.08 30.16 ± 11.11 30.16 ± 11.11 0.135 0.079 0.153
Standing 20.94 ± 13.08 21.79 ± 13.53 22.22 ± 13.93 0.156 29.40 ± 9.70 31.11 ± 9.90 31.79 ± 10.04 0.076 0.866 0.440
Walking/Running/Jumping 16.67 ± 11.08 16.90 ± 11.31 17.36 ± 11.51 0.156 23.70 ± 8.69 25.46 ± 9.05 27.69 ± 9.44 0.003** 0.968 0.083
Total 31.85 ± 8.93 32.13 ± 9.04 32.37 ± 9.13 0.030* 39.11 ± 8.86§ 40.73 ± 8.93 41.37 ± 9.06§ 0.000*** 0.938 0.030*

p value: *< 0.05, **< 0.01, ***< 0.001

pa: Comparison between three assessing time points, Friedman's two-way analysis of variance

pb: Comparison between the group of Rett syndrome and CP at baseline, Mann–Whitney Test

pc: Comparison of the alteration from baseline to 12 weeks between the group of Rett syndrome and CP, GEE

§: Comparison between baseline and 12th week, p value: < 0.05, multiple comparison of Friedman's two-way analysis of variance

CP Cerebral palsy, RETT Rett syndrome, SEM standard error of the mean, MAS Modified Ashworth Scale, PROM Passive range of motion, GMFM Gross motor function measure