Table 3.

Main genetically engineered virus strains

Oncolytic virus	Viral structures	Critical pathway of specific infections in tumors	Partial genetically engineered oncolytic virus strains	References
Herpes simplex virus	Linear double-stranded DNA virus	Interferon signaling pathway	NV1020, G207, HF-10, HSV-1716, T-VEC, G47∆, M032, RP1, RP2, R36166, DM33, C134	[20, 21, 25]
Newcastle disease virus	Single-stranded RNA virus	Interferon signaling pathway	Lasota, Anhinga, Mukteswar	[28–31]
Vaccinia virus	Linear double-stranded DNA virus	EGFR-Ras signaling pathway	Wyeth, Lister, Copenhagen, Western Reserve, Tian Tan, Modified, Vaccinia Ankar	[41, 42]
Measles virus	Single-stranded RNA virus	Density differences of CD46, SLAM and Nectin-4 receptors	MV-CEA, MV-NIS	[39]
Adenovirus	Linear double-stranded DNA virus	Rb and p53 cell signaling pathway	H101, ONYX-105, DNX-2401, LOAD703, VCN-01, OBP-301, ONCOS-102	[44, 45, 95]