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. Author manuscript; available in PMC: 2024 Jan 3.
Published in final edited form as: ACS Chem Neurosci. 2022 Apr 28;13(10):1534–1548. doi: 10.1021/acschemneuro.2c00033

Figure 8. Effects of DAT blockers on dopamine release and uptake kinetics in vivo.

Figure 8.

Time course of psychostimulants on dopamine transmission across 30 minutes (post-injection) as measured by A) peak height, upward velocity (inset), B) ratio of upward velocity to peak height, C) exponential decay (tau), and E) downward velocity for WF23 (black), PTT (purple), and cocaine (pink). All values normalized to baseline. D) Comparison of tau (normalized) to ratio of upward velocity to peak height for each drug across the full time course. F) Comparison of downward velocity (normalized) to tau (normalized) for each drug.