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. 2023 Dec 26;165(2):bqad193. doi: 10.1210/endocr/bqad193

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Figure 4. — Identification of differentially expressed genes and pathways by RNA sequencing in AR^cKO mesonephroi. A, Volcano plot displaying gene expression at E14.5. Differentially expressed genes (DEGs; adjusted P values <.1) in the AR^cKO group are highlighted in blue (downregulated genes) and red (upregulated genes), respectively. B, Gene ontology (GO) analysis showing enriched cellular components and biological processes associated with DEGs. C, Dot plots illustrating the expression levels of 4 selected genes (Ar, Top2a, Wnt9b, and Lama2). All 4 genes were significantly downregulated in the AR^cKO group. TMP, transcripts per million.