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. 2024 Jan 2;25:3. doi: 10.1186/s13059-023-03126-1

Table 1.

A comparison of features across FORGEdb, HaploReg and RegulomeDB

FORGEdb HaploReg RegulomeDB
Roadmap chromatin states Yes Yes Yes
TF motifs Yes Yes Yes
SNP scoring system Yes No Yes
Roadmap DNase-seq Yes Yes No
Roadmap H3 histone mark data Yes Yes No
SiPhy cons No Yes No
caQTLs No No Yes
3D genomic data (ABC Hi-C-based data) Yes No No
CADD v1.6 data across different alleles Yes No No
GTEx v8 allele-specific association data Yes No No
eQTLGen allele-specific association data Yes No No
BLUEPRINT DNase-seq Yes No No
Allele-specific TF binding data (CATO) Yes No No
Zoonomia allele-specific conservation data Yes No No
ENCODE4 regulatory element CRISPR sgRNAs Yes No No