TABLE 3.

Univariable Analyses for Diagnostic Yield.

Variable	Forceps biopsy		Cryobiopsy		Overall diagnostic yield
	Diagnostic yield (%)	P	Diagnostic yield (%)	P	Diagnostic yield (%)	P
Age (y)
≤70	70/105 (66.7)	0.675	90/105 (85.7)	0.742	96/105 (91.4)	0.988
>70	60/94 (63.8)		79/94 (84.0)		86/94 (91.5)
Sex
Male	75/117 (64.1)	0.665	103/117 (88.0)	0.143	108/117 (92.3)	0.608
Female	55/82 (67.1)		66/82 (80.5)		74/82 (90.2)
Smoking history
Never	56/88 (63.6)	0.656	71/88 (80.7)	0.136	80/88 (90.9)	0.805
Ever	74/111 (66.7)		98/111 (88.3)		102/111 (91.9)
Diameter of lesion (mm)
≤20	31/61 (50.8)	0.004	50/61 (82.0)	0.438	52/61 (85.2)	0.037
>20	99/138 (71.7)		119/138 (86.2)		130/138 (94.2)
Diameter of lesion (mm)
<10mm	4/8 (50.0)	0.010	6/8 (75.0)	0.439	6/8 (75.0)	0.012
10-20 mm	30/59 (50.8)		48/59 (81.4)		50/59 (84.7)
>20 mm	96/132 (72.7)		115/132 (87.1)		126/132 (95.5)
Diameter of lesion in lower lobes (mm)
<10mm	4/6 (66.7)	0.220	6/6 (100)	0.350	6/6 (100)	0.250
10-20 mm	16/28 (57.1)		23/28 (82.1)		25/28 (89.3)
>20mm	38/51 (74.5)		46/51 (90.2)		49/51 (96.1)
Location of lesion
RUL and LUS	50/81 (61.7)	0.377	63/81 (77.8)	0.02	69/81 (85.2)	0.009
Others	80/118 (67.8)		106/118 (89.8)		113/118 (95.8)
Morphology
Others	31/49 (63.3)	0.727	34/49 (69.4)	<0.001	42/49 (85.7)	0.098
Solid	99/150 (66.0)		135/150 (90.0)		140/150 (93.3)
CT bronchus sign
Positive	124/188 (66.0)	0.440	161/188 (85.6)	0.219	174/188 (92.6)	0.056
Negative	6/11 (54.5)		8/11 (72.7)		8/11 (72.7)
EBUS orientation
Within	98/139 (70.5)	0.017	112/139 (87.8)	0.199	133/139 (95.7)	0.002
Adjacent	30/57 (52.6)		46/57 (80.7)		47/57 (82.5)
Number of cryobiopsies
1	NA		53/68 (77.9)	0.047	62/68 (91.2)	0.919
>1			116/131 (88.5)		120/131 (91.6)
Pathology
Malignancy	102/158 (64.6)	0.654	130/158 (82.3)	0.049	141/158 (89.2)	0.026
Benign	28/41 (65.3)		39/41 (95.1)		41/41 (100)

Data are presented as number (%).

CT indicates computed tomography; EBUS, endobronchial ultrasound; LUS, left upper segment; RUL, right upper lobe.