Figure 5. STED super-resolution microscopy of human DCM and normal control cardiac muscle samples.

Representative STED images of DCM^TTNtv+ (A), DCM^TTNtv– (B), and normal control (CTRL) (papillary muscle) (C) cardiac samples labeled with MIR and A170 antibodies. Arrows point to the MIR epitopes within 1 cardiac sarcomere, and arrowheads indicate the A170 epitopes near the M-line of the same sarcomere. Note that no gross structural alterations can be discerned in the DCM^TTNtv+ sarcomeres. Scale bars: 2 μm.