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. 2023 Dec 13;13(1):2295387. doi: 10.1080/22221751.2023.2295387

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© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 2. — Transcriptional patterns of peripheral blood mononuclear cells (PBMC) defining PPD-stimulated and un-stimulated of HHC-1 and HHC-23 group. RNA-seq were performed using 4 and 8 (4 from HHC-2 and 4 from HHC-3) PBMC samples from HHC-1 and HHC-23 group, respectively. A. Principal component analysis diagram. B. Venn diagrams showing overlaps of TB-specific genes changes between HHC-1 and HHC-23 group. Unsupervised hierarchical clustering of transcribed genes and differentially expressed over 1.5-fold of PPD-stimulated (C) and unstimulated samples (D). Volcano plot shows the upregulated and downregulated transcribed genes between HHC-1 and HHC-23 group of PPD-stimulated (E) and unstimulated samples (F).