Table 2. Characteristics of the three analytical (unrelated, European ancestry) datasets*.
| MGI | UKB | All of Us | |
|---|---|---|---|
| n | 47257 | 425787 | 47401 |
| Age | |||
| mean (SD) | 59.18 (16.44) | 61.11 (9.09) | 59.26 (16.73) |
| categories, n (%) | |||
| [18,35) | 4827 (10.2) | 0 (0.0) | 5384 (11.4) |
| [35,50) | 8337 (17.6) | 60461 (14.2) | 8736 (18.4) |
| [50,65) | 14638 (31.0) | 200090 (47.0) | 12624 (26.6) |
| [65,80) | 15454 (32.7) | 165223 (38.8) | 16814 (35.5) |
| >=80 | 4001 (8.5) | <20 (<0.005) | 3843 (8.1) |
| Female (%) | 22398 (47.4) | 229753 (54.0) | 28608 (60.4) |
| BMI | |||
| mean (SD) | 29.95 (7.09) | 27.40 (4.77) | 29.10 (7.07) |
| categories, n (%) | |||
| Underweight (< 18.5) | 505 (1.1) | 2180 (0.5) | 514 (1.1) |
| Healthy weight [18.5, 25) | 11403 (24.1) | 138770 (32.6) | 13782 (29.1) |
| Overweight [25, 30) | 15282 (32.3) | 180589 (42.4) | 15171 (32.0) |
| Obese (>= 30) | 20041 (42.4) | 102929 (24.2) | 17221 (36.3) |
| n/a | 26 (0.1) | 1319 (0.3) | 713 (1.5) |
| Individuals without Recorded Diagnoses, n (%) | 0 (0) | 74836 (17.6) | 10859 (22.9) |
| Age at first recorded diagnosis, mean (SD) | 47.57 (17.04) | 52.64 (10.34) | 47.71 (16.52) |
| Age at last recorded diagnosis, mean (SD) | 59.18 (16.44) | 60.91 (10.23) | 58.00 (16.74) |
| Elixhauser AHRQ, mean (SD) | 8.42 (14.11) | 1.67 (5.30) | 2.29 (8.57) |
| Elixhauser AHRQ binned, n (%) | |||
| <0 | 12245 (25.9) | 69767 (16.4) | 11606 (24.5) |
| 0 | 5931 (12.6) | 254344 (59.7) | 20573 (43.4) |
| 1-4 | 5045 (10.7) | 31309 (7.4) | 4281 (9.0) |
| >=5 | 24036 (50.9) | 70367 (16.5) | 10941 (23.1) |
| Number of unique PheCodes per Person, mean (SD) | 67.09 (59.74) | 8.83 (11.25) | 31.89 (40.22) |
| Hospitalized with COVID-19, n (%)** | 217 (0.46) | 2560 (0.60) | 298 (0.63) |
* MGI: data from before 2020-02-13; All of Us: data from before 2020-03-11; UK Biobank: data from before 2018 (last observed date March 2017)
** MGI: COVID-19 data from before March 2023; All of Us: data from before 2022-01-01; UK Biobank: data from before February 2023.
Abbreviations: AHRQ, Agency for Healthcare Research and Quality; MGI, Michigan Genomics Initiative; SD, standard deviation; UKB, UK Biobank