Table 2. % Cell Viability (IC₅₀) of the Active Analogues of Compounds (5a–t) against Brain Cancer (U87) and Normal (HEK293) Cell Lines.

compds	concentration	% cell viability U87	% cell viability HEK293	IC50 (μM ± SEM U87)
4	10	72.48	29.06	59.9 ± 0.08
	40	47.92	28.63
	80	41.59	28.20
	100	41.29	26.30
	150	33.69	9.96
5a	10	89.95	49.34	36.70 ± 0.14
	40	88.02	48.55
	80	77.41	47.25
	100	73.86	45.20
	150	61.75	38.29
5b	10	80.51	111.70	35.73 ± 0.09
	40	75.83	101.63
	80	70.36	95.98
	100	62.23	94.29
	150	59.10	91.18
5c	10	119.53	58.63	62.89 ± 0.15
	40	108.60	55.19
	80	107.07	49.58
	100	106.67	49.52
	150	94.78	47.63
5d	10	55.95	64.08	122.46 ± 0.14
	40	51.96	55.95
	80	40.37	49.81
	100	27.60	43.64
	150	22.08	39.42
5e	10	43.42	69.42	5.75 ± 0.43
	40	41.01	69.09
	80	39.87	67.88
	100	28.47	62.10
	150	27.48	50.83
5f	10	54.09	102.53	24.17 ± 0.46
	40	44.25	79.22
	80	38.69	71.94
	100	28.96	69.91
	150	21.62	63.50
5g	10	56.40	86.66	39.94 ± 0.16
	40	47.40	75.46
	80	39.45	62.21
	100	33.32	62.12
	150	30.90	56.11
5h	10	50.20	84.13	120.07 ± 0.13
	40	50.15	79.45
	80	48.83	69.13
	100	45.96	68.32
	150	43.63	67.09
5i	10	40.32	67.56	38.32 ± 0.10
	40	36.85	57.35
	80	31.43	55.73
	100	29.86	49.92
	150	24.43	43.82
5j	10	186.64	44.54	43.71 ± 0.07
	40	128.08	40.06
	80	94.20	38.35
	100	93.14	36.79
	150	78.60	26.31
5k	10	121.23	42.15	52.81 ± 0.06
	40	100.37	35.61
	80	99.04	28.64
	100	96.61	25.74
	150	90.20	25.47
5l	10	96.97	30.48	72.83 ± 0.06
	40	88.44	28.12
	80	84.89	25.92
	100	84.18	24.86
	150	79.72	24.19
5m	10	141.99	26.18	150.45 ± 0.20
	40	138.25	26.12
	80	34.46	24.16
	100	134.23	21.90
	150	127.60	18.62
5n	10	164.68	38.13	40.18 ± 0.07
	40	85.29	27.99
	80	61.13	24.79
	100	42.70	16.88
	150	33.17	12.62
5o	10	146.33	49.04	119.73 ± 0.25
	40	121.87	42.87
	80	120.97	37.72
	100	119.00	35.75
	150	106.95	35.19
5p	10	150.92	49.89	90.68 ± 0.13
	40	121.78	49.35
	80	93.71	49.16
	100	93.65	48.09
	150	93.46	39.27
5q	10	182.99	27.52	46.0 ± 0.08
	40	84.04	25.39
	80	81.65	19.95
	100	48.50	19.70
	150	40.48	17.80
5r	10	109.42	39.02	43.66 ± 0.04
	40	81.40	33.62
	80	72.77	31.98
	100	45.45	26.11
	150	40.62	25.06
5s	10	145.03	58.72	43.73 ± 0.11
	40	93.13	58.38
	80	92.16	51.45
	100	78.36	49.00
	150	69.18	39.29
5t	10	179.1	68.74	86.74 ± 0.26
	40	169.25	58.86
	80	155.44	51.05
	100	146.07	47.32
	150	139.58	43.01