Probability of (A) EFS and (B) OS for patients according to the treatment Cohort, (C) EFS and (D) OS for stage 4 patients in Cohort 1 with and without an end-induction metastatic CR, (E) EFS and (F) OS for patients in Cohort 2 according to the overall INRC response at end-of-bridge therapy, and (G) EFS and (H) OS for patients in Cohort 2 with and without a metastatic CR at end-of-bridge therapy. CR indicates complete response; EFS, event-free survival; INRC, International Neuroblastoma Response Criteria; OS, overall survival; PR, partial response.