TABLE 1.
Demographic and clinical characteristics of patients with liver fibrosis before antiviral therapy.
| Group | Regression group (n = 30) | Non-regression group (n = 30) | Statistics | p-value |
|---|---|---|---|---|
| Male/female, n | 20/10 | 20/10 | — | — |
| Age (y) | 43 ± 7.33 | 42.67 ± 9.65 | 0.151 | 0.248 |
| BMI | 23.54 ± 2.58 | 24.38 ± 2.95 | −1.164 | 0.881 |
| ALT (IU/L) | 39 (26, 63.05) | 40 (24.75, 60.35) | −0.126 | 0.9 |
| AST (IU/L) | 38.5 (29, 49.1) | 50.45 ± 27 | −0.547 | 0.584 |
| Alb (g/L) | 44.25 (41.03, 47) | 41.5 (37.13, 45.23) | 1.382 | 0.167 |
| TBIL (μmol/L) | 12.95 (9.25, 18.51) | 13.35 (10.13, 18.2) | −0.266 | 0.79 |
| GGT (IU/L) | 77.9 ± 68.19 | 75.07 ± 52.78 | 0.18 | 0.858 |
| ALP (IU/L) | 100.17 ± 25.77 | 92.81 ± 33.9 | 0.918 | 0.363 |
| Cr (μmol/L) | 70.73 ± 16.03 | 70.8 ± 20.38 | −0.014 | 0.989 |
| WBC (×109/L) | 5.35 ± 1.8 | 4.66 ± 1.2 | 1.713 | 0.093 |
| HGB (g/L) | 141 (137, 151) | 140 (131.5, 148.5) | −0.845 | 0.398 |
| PLT (×109/L) | 128.37 ± 54.58 | 104.89 ± 35.73 | 1.763 | 0.06 |
| PT (s) | 12.53 ± 1.49 | 13.55 ± 1.69 | −0.044 | 0.965 |
| TC (mmol/L) | 4.16 ± 0.94 | 4.15 ± 1.04 | 0.026 | 0.979 |
| TG (mmol/L) | 1.14 ± 0.45 | 0.94 (0.67, 1.16) | 1.678 | 0.093 |
| HDL-CH (mmol/L) | 1.3 ± 0.38 | 1.42 ± 0.33 | −1.292 | 0.201 |
| LDL-CH (mmol/L) | 2.56 ± 0.89 | 2.41 ± 0.95 | 0.62 | 0.538 |
| Blood glucose (mmol/L) | 5.16 ± 0.85 | 5.26 ± 7.9 | −0.427 | 0.672 |
| AFP (μg/L) | 6.98 (3.48, 20.33) | 8.48 (3.88, 22.56) | −0.118 | 0.906 |
| Positive HBeAg, n, % | 13 (43.33) | 14 (46.67) | 0.067 | 0.795 |
| Log10 HBV DNA (IU/mL) | 4.84 ± 2.17 | 4.46 ± 1.85 | 0.326 | 0.471 |
| Ishak score | 0 | 1 | ||
| F5, n, % | 14 (46.67) | 14 (46.67) | ||
| F6, n, % | 16 (53.33) | 16 (53.33) |
Mean values are provided with SD, and medians are provided with quartiles (Q1, Q3).
Annotations: BMI, body mass index; ALT, alanine aminotransferase; AST, aspartate aminotransferase; Alb, Albumin; TBIL, total bilirubin; GGT, γ-glutamyl transpeptidase; ALP, alkaline phosphatase; Cr, Creatinine; WBC, white blood cell; HGB, hemoglobin; PLT, platelet count; PT, prothrombin time; TC, total cholesterol; TG, triglyceride; HDL-CH, High-density lipoprotein cholesterol; LDL-CH, Low-density lipoprotein cholesterol; AFP, alpha fetoprotein.