TABLE 2.

Identification of biomarkers for regression and non-regression groups.

No.	Metabolite	Class	HMDB	KEGG	R vs NR
					log2 FC	VIP	p-value
1	Homoserine	Amino acids	HMDB0000719	C00263	−0.457	2.299	0.003
2	Oxoadipic acid	Organic acids	HMDB0000225	C00322	0.141	1.08	0.003
3	Ornithine	Amino acids	HMDB0000214	C00077	−0.427	0.754	0.011
4	Tartaric acid	Carbohydrates	HMDB0000956	C00898	0.122	1.029	0.011
5	m-Aminobenzoic acid	Benzoic acids	HMDB0001891	NA	0.042	1.179	0.016
6	Formic acid	SCFAs	HMDB0000142	C00058	0.051	1.362	0.019
7	Arachidonic acid	Fatty acids	HMDB0001043	C00219	0.5	1.589	0.022
8	Threonine	Amino acids	HMDB0000167	C00188	−0.214	1.457	0.028
9	EPA	Fatty acids	HMDB0001999	C06428	0.825	1.517	0.032
10	Dihomo-gamma-linolenic acid	Fatty acids	HMDB0002925	C03242	0.913	1.184	0.033
11	DHA	Fatty acids	HMDB0002183	C06429	0.511	1.34	0.041
12	DPA	Fatty acids	HMDB0006528	C16513	0.636	1.279	0.046
13	Adrenic acid	Fatty acids	HMDB0002226	C16527	−0.424	0.547	0.048

Annotations: FC, fold change; R, regression group; NR, Non-regression group; EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid; DPA, docosapentaenoic acid.