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. 2023 Dec 21;14:1329266. doi: 10.3389/fphar.2023.1329266

TABLE 3.

Demographic and clinical data of the validation cohort.

Validation patients Regression group (n = 36) Non-regression group (n = 36) p-value
Male/female 22/14 22/14
Age (y) 43 ± 6.75 43 ± 8.75 0.894
BMI 23.75 ± 2.36 23.21 ± 2.62 0.397
ALT (IU/L) 40.74 ± 23.28 34.5 (25, 57.58) 0.702
AST (IU/L) 30.5 (24, 51.25) 36.50 (30, 53.13) 0.213
Alb (g/L) 43.03 ± 5.46 41.85 ± 6.15 0.695
TBIL (μmol/L) 13.43 ± 6.86 11.3 (8.13, 19.14) 0.724
Cr (μmol/L) 65.35 ± 16.95 68.25 ± 14.55 0.478
WBC (×109/L) 4.62 (3.41, 6.04) 4.52 ± 1.63 0.444
HGB (g/L) 145 (126.5, 157.1) 139.44 ± 18.23 0.608
PLT (×109/L) 121.83 ± 56.6 115.41 ± 57.15 0.665
PT (s) 13.32 ± 1.5 13.5 (12.4, 14) 0.568
TC (mmol/L) 4.09 ± 0.99 4.21 ± 1.05 0.659
TG (mmol/L) 1.05 (0.82, 1.29) 1.16 ± 0.49 0.534
HDL-CH (mmol/L) 1.38 ± 0.4 1.42 ± 0.41 0.735
LDL-CH (mmol/L) 2.39 ± 0.82 2.44 ± 0.79 0.808
Blood glucose (mmol/L) 5.01 ± 0.57 5.3 (4.56, 6.17) 0.09
AFP (ng/mL) 12.46 ± 13.22 23.70 ± 59.55 0.082
Positive HBeAg, n, % 19 (52.7%) 15 (41.5%) 0.345
Log10 HBV DNA (IU/mL) 4.35 ± 1.79 4.98 ± 2 0.197
Ishak score (n, %) 0.471
F5 23 (63.8%) 20 (55.6%)
F6 13 (36.1%) 16 (44.4%)

Annotations: BMI, body mass index; ALT, alanine aminotransferase; AST, aspartate aminotransferase; Alb, Albumin; TBIL, total bilirubin; GGT, γ-glutamyl transpeptidase; ALP, alkaline phosphatase; Cr, Creatinine; WBC, white blood cell; HGB, hemoglobin; PLT, platelet count; PT, prothrombin time; TC, total cholesterol; TG, triglyceride;HDL-CH, High-density lipoprotein cholesterol; LDL-CH, Low-density lipoprotein cholesterol; AFP, alpha fetoprotein.