Table 3.
Results of screening for known driver genes
| Gene | Chrom | Ref | Alt | Classification | AA change |
|---|---|---|---|---|---|
| PREX2 | chr8 | – | T | Frame_Shift_Ins | p.S565fs |
| KDM6A | chrX | G | – | Frame_Shift_Del | p.A694fs |
| PTPRC | chr1 | C | T | Nonsense_Mutation | p.Q1036* |
| LTBP1 | chr2 | C | T | Intron | – |
| EBF1 | chr5 | G | A | Intron | – |
| DST | chr6 | A | C | Intron | – |
| EEF1A1 | chr6 | C | G | Missense_Mutation | p.E268Q |
| CARD11 | chr7 | G | A | Silent | p.I398I |
| AMPH | chr7 | G | A | 5'UTR | – |
| TRIM24 | chr7 | C | G | Intron | – |
| PDCD1LG2 | chr9 | G | A | Missense_Mutation | p.R181H |
| MAPK8IP1 | chr11 | G | A | Intron | – |
| ZBTB16 | chr11 | G | A | Missense_Mutation | p.M348I |
| KRAS | chr12 | C | A | Missense_Mutation | p.G12V |
| MGA | chr15 | C | G | Silent | p.L2623L |
| TP53 | chr17 | C | T | Missense_Mutation | p.E285K |
| ZNF521 | chr18 | C | T | Silent | p.A182A |
| TSHZ3 | chr19 | C | T | Silent | p.S837S |
| DMD | chrX | G | A | Intron | – |
Chrom chromosome, REF reference base, ALT alternative base, AA change information on amino acid changes