Table 1:
Demographic characteristics of the whole cohort.
| Variablea | Patients (n = 230) |
|---|---|
| Age at ES (years) | 47.5 [36.8–62] |
| Age at kidney disease onset or discovery | 35 [23–50] |
| Male | 133 (57.8) |
| Geographic origin | |
| Europe | 173 (75.2) |
| North Africa | 31 (13.5) |
| Sub-Saharan Africa | 12 (5.2) |
| French Antilles | 7 (3.1) |
| Asia | 2 (0.01) |
| Others | 5 (2.2) |
| Consanguinity | 25 (10.9) |
| Kidney disease onset before 35 years old | 126 (54.8) |
| With familial history | 50 (21.7) |
| Familial history of kidney disease | 115 (50) |
| First degree only | 58 (25.2) |
| Second degree only | 19 (8.3) |
| Both first and second degree | 37 (16.2) |
| Prior negative genetic exploration with gene panel | 34 (14.7) |
| ES first to avoid kidney biopsy | 22 (9.5) |
| Prior inconclusive kidney biopsy | 69 (30.1) |
| Kidney disease discovered at ESKD | 43 (18.7) |
| Impossible kidney biopsy | 71 (30.9) |
| Undetermined clinical nephropathy subgroup | |
| Unclassified | 88 (38.3) |
| Glomerular | 64 (27.8) |
| Tubulointerstitial | 30 (13) |
| Cyst | 32 (13.9) |
| Vascular | 16 (7) |
| Stage of kidney disease at ES | |
| I | 32 (13.9) |
| II | 13 (5.7) |
| III | 39 (17) |
| IV | 32 (13.9) |
| V | 22 (9.5) |
| V (D) | 54 (23.5) |
| V (T) | 38 (16.5) |
| Status of patient transplantation | 80 (34.5) |
| Active in transplant waiting list | 16 (6.9) |
a
For quantitative variables, values are expressed as median [interquartile ranges]. For qualitative variables, values are expressed as n (%).