Table 1.
Clinical and laboratory characteristics of the patients with GPA at the time of blood sampling
| GPA | |
|---|---|
| Subjects, n (% male) | 27 (44%) |
| Age, mean (range) | 61 (34–79) |
| PR3-ANCA positivea, n (% positive) | 18 (67%) |
| Localized/generalized disease, n (% generalized) | 6/21 (78%) |
| CRP (mg/l), median (range) | 5.8 (<0.3–11) |
| eGFRb ml/min/1.73 m2, median (range) | 64 (15–91) |
| Disease duration in years, median (range) | 9.5 (1.3–30.8) |
| Number of previous relapses, median (range) | 1 (0–6) |
| Non/maintenance immunosuppressive therapyc, n | 19/8 |
a
ANCA-positive titre ≥1:40, ANCA-negative ≤1:20.
b
Estimated Glomerular Filtration Rate (eGFR) was calculated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation.
c
Immunosuppressive maintenance therapy: AZA, AZA + prednisolone, or prednisolone.