The expression of angiogenesis-related markers (A, C) and immunohistochemical staining (B, D) of the bone defect area after β-TCP、Sr5TCP、Sr10 TCP and Sr20 TCP scaffolds were implanted into the bone defect for 1 week and 4 weeks. * Represents a significant difference compared to Β-TCP group, *p < 0.05, **p < 0.01, ***p < 0.001; E-The effect of SrTCP with different strontium doping contents on micro-vessels formation: HE staining after 4 and 8 weeks of scaffold implantation (black arrows indicate the generated micro-vessels).