Fig. 15.

Illustration of enhancing immunotherapy by Ferroptosis in coordination with SDT. a) Scheme of CS-ID@NMs as multi-functional motors achieved efficient mucus-traversing ability, deep tumor penetration and potentiation of antitumor immunity. b) Immunofluorescence staining of CD4⁺ CD8⁺ T cells, Foxp3⁺ cells and quantitative analysis of c) CD4⁺ CD8⁺ T cells and d) Foxp3⁺ cells in the tumors after various treatments. Reprinted with permission from Ref. [167]. Copyright 2022, Wiley-VCH.