Tab. 3: Chemicals tested for CYP26A1 and/or CYP26B1 inhibition in selected publications.

For (Foti et al., 2016b), the 17 chemicals that passed the single concentration inhibition screen are listed in addition to results for known CYP26 inhibitors. For all chemicals, consult the publications for measured values, experimental conditions, and cut-offs used.

	Thatcher et al., 2011	Foti et al., 2016a		Foti et al., 2016b		Buttrick, 2013
Chemical	CYP26A1	CYP26A1	CYP26B1	CYP26A1	CYP26B1	CYP26A1	CYP26B1
17-alpha-ethinyl estradiol				X	X
AM580		X	X			X	X
AM80 (tamibarotene)		X	X	X	X	X	X
Benzbromarone				X	X
Bexarotene				X	X	X	X
BMS753		X	X			X	X
BMS961		X	X			X	X
Candesartan				X	X
Candesartan cilexetil				X	X
CD1530	X
CD437				X	X
Clotrimazole				X	X
CS5	X
EC23				X	X	X	X
Fluconazole				X	X
Itraconazole				X	X
Ketoconazole	X			X	X	X	X
L-165,041	X
Liarozole	X			X	X	X	X
MM11253				X	X	X	X
Mometasone				X	X
Montelukast				X	X
Pioglitazone	X			X	X
Quercetin				X	X
R115866 (talarozole)	X			X	X	X	X
R116010	X					X	X
Raloxifene				X	X
Repaglinide				X	X
Ritonavir				X	X
Rosiglitazone	X			X	X
SR11237				X	X	X	X
Tamoxifen				X	X
Tazarotene						X	X
Tazarotenic acid (Agn 190299)		X	X			X	X
TTNPB	X	X	X			X	X
Zafirlukast				X	X