Table 3.
Relative treatment effect comparisons (95% CI) for cardiovascular death (upper triangle) and all-cause mortality (lower triangle).
Standard of care | 0.89 (0.62, 1.27) | 0.95 (0.71, 1.27) | 0.92 (0.78, 1.09) | 0.88 (0.74, 1.06) | 0.78 (0.57, 1.06) |
---|---|---|---|---|---|
0.86 (0.63, 1.18) | Sotagliflozin | 1.07 (0.67, 1.69) | 1.04 (0.70, 1.54) | 0.99 (0.66, 1.49) | 0.87 (0.55, 1.40) |
0.97 (0.75, 1.25) | 1.12 (0.75, 1.67) | Ertugliflozin | 0.98 (0.70, 1.36) | 0.93 (0.66, 1.31) | 0.82 (0.54, 1.25) |
1.01 (0.86, 1.17) | 1.17 (0.82, 1.65) | 1.04 (0.77, 1.40) | Empagliflozin | 0.96 (0.75, 1.22) | 0.84 (0.59, 1.19) |
0.84* (0.72, 0.98) | 0.97 (0.69, 1.38) | 0.87 (0.64, 1.17) | 0.83 (0.67, 1.04) | Dapagliflozin | 0.88 (0.62, 1.26) |
0.76 (0.58, 1.00) | 0.88 (0.58, 1.33) | 0.78 (0.54, 1.14) | 0.75 (0.55, 1.03) | 0.90 (0.66, 1.24) | Canagliflozin |
Comparison should be read from right to left. In the upper rectangle, a relative risk of <1 favors the drug in the column. In the lower rectangle, a relative risk of <1 favors the drug in the row.
*Statistical significance.